CERTIFICATION
Published on April 28, 2022
Exhibit 31.1
Certification of Chief Executive Officer
I, James N. Woody, M.D., Ph.D., certify that:
| 1. | I have reviewed this annual report on Form 10-K/A for the year ended December 31, 2021, of 180 Life Sciences Corp. (the “registrant”); and |
| 2. | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. |
| Date: April 28, 2022 | |
| /s/ James N. Woody, M.D., Ph.D. | |
| James N. Woody, M.D., Ph.D. | |
| Chief Executive Officer (Principal Executive Officer) |